| About
us
|
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Consulting
in Drug Design GbR (CDD) was established in 1992 by Prof. Dr. habil. Rainer
Franke (curriculum vitae R.
F. ) and DC Andreas Gruska (curriculum
vitae A. G.). It is built on the knowledge of more than 20 years of
academic research in Computer Aided Drug Design and Medicinal Chemistry
at the former Institute of Drug Research of the Academy of Sciences of
the GDR, and on a long tradition of cooperation with the pharmaceutical
and agrochemical industry. Customers
of CDD are major pharmaceutical and agrochemical companies in Europe but
also academic and government institutions. CDD
has special know how in the application of chemometric
methods in Drug Design and computational risk assessment (see also publications).
Prof.
R. Franke and DC A. Gruska are both physical chemists with specialization
in biochemistry, pharmacology, and pharmaceutical as well as agrochemical
research. During their careers, they have been involved in the following
research areas:
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Development
and application of chemometric methods of structure-activity analysis (QSAR)
for bioactive agents |
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therapeutics
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agrochemicals |
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toxicants
and carcinogens |
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Biochemical
measurements. |
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Standardization
of biochemical and biological tests. |
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Application
of physicochemical methods to derive descriptors for drug design |
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water
solubility |
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protein
binding |
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polarography |
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partition
coefficients |
| They
had lectureships at several universities in biochemistry, medicinal chemistry,
and drug design (Medical Academy Carl-Gustav-Carus, Dresden; Humboldt University,
Berlin; Martin-Luther University, Halle/Wittenberg; Free University, Berlin;
Ernst-Moritz-Arndt University, Greifswald; Company Academy of VEB Berlin
Chemie) and were involved in the organization of national and international
conferences (e.g., European QSAR conferences) and courses (e.g., International
Course on DRUG DESIGN IN LEAD OPTIMIZATION, Leiden/Amsterdam Center for
Drug Research, 1996) in the field of drug design. |
