Seminars and Training
CDD offers seminars and courses in all aspects of the application of chemometrics to the discovery of new drugs. Not only can these be tailored to the specific requirements of the host company, they can also be devised for audiences whose level of knowledge and needs are different:
Management/research scientists in general.
Medicinal chemists/pharmacologists/biologists who are interested to have Drug Design methods applied to their results and to use results from Drug Design for their work.
Research scientists involved or planning to become involved in Drug Design with primary experience in molecular modeling and related techniques (including interested crystallographers, NMR specialists etc.).
The seminars are based on a modular system (see below) where each module can be presented at different levels depending on the experience of the participants. The modules are largely independent from each other and can be combined in various ways. Practical examples are given a high importance emphasizing, for each type of approach
when to be applied in practice and why
benefits
limitations and pitfalls
practical experiences
interaction with other approaches.
CDD list of seminar modules:
General introduction into QSAR: methods, experiences, and industrial application
Biological response parameters
Parameters and models to describe chemical properties of biologically active compounds
Multiple regression analysis I: Hansch analysis
Multiple regression analysis II: Free-Wilson analysis
Series design and compound selection
Principal component and factor analysis
Principal component regression and PLS
Cluster and cluster significance analysis
Methods to treat classified data
3D QSAR
Neural nets and genetic algorithms
Approaches with substructural descriptors
Chemical diversity
Seminars or courses are usually provided at the customer site. In addition, an individual training including practical exercises is available at CDD. Experience has shown that a very successful way to deliver this type of training is to make use of presolved examples from the companies own research portfolio.
CDD has experience in providing seminars and training to industrial customers. In addition to a number of courses at industry sites CDD scientists have been involved in academic teaching as well as national and international seminars (see about us).